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Ironnox Logo
Advanced Liposomal Iron
Blood Vessel Illustration

Iron: The Essential Mineral

Iron is a vital mineral necessary for producing hemoglobin, the protein in red blood cells that transports oxygen throughout the body, a process crucial for cellular energy and overall vitality.

Traditional iron supplements often face absorption challenges and may cause side effects, making it important to understand different iron salt forms.

Iron in its ferrous state (Fe2+) is directly absorbed in the intestine, whereas ferric salts (Fe3+) must be converted to the absorbable ferrous form in the intestinal mucosa, ensuring effective uptake.

The Bioavailability Challenges

Low Absorption

Conventional ferrous iron salts are poorly absorbed in the gut.

Antioxidants

Oxidative Stress

Unabsorbed iron undergoes oxidation, generating reactive oxygen species (ROS) that damage the intestinal epithelium.

Immunity

Poor Palatability

Unpleasant metallic taste and aftertaste reduce patient compliance.

Aging

GI Discomfort

Leads to gastrointestinal irritation and limits efficacy, leaving deficiency unresolved.

Skin

Absorption Inhibitors

Dietary components such as phytates, tannins, calcium, and oxalates interfere with iron absorption.

Collagen

The   Advantage

IRONNOX™ combines DFS Technology™ (Dietary Fiber Stabilized) with liposomal encapsulation to protect iron during digestion, ensuring optimal absorption, targeted delivery, and high bioavailability.

This advanced formulation prevents metallic aftertaste and gastric discomfort, providing a neutral-tasting, stable & effective supplement.

Backed by Science, Proven in Research

TEM Analysis:

Confirms uniform nanosize liposomes with well-defined structure.

Zeta Potential:

Demonstrates excellent formulation stability.

Cellular Uptake Study (Caco-2 model):

Liposomal iron salts show about 2× higher permeability than conventional iron.

Third-Party Validation

University of Barcelona tested IRONNOX™ vs a leading competitor's liposomal iron

⊙ IRONNOX™: Uniform liposomes fully encapsulating iron for optimal delivery
⊙ Competitor: Liposomes present but empty, iron dispersed outside as an emulsion
Grade/Specification
Available Forms
  • • Ferrous Ascorbate: 7.5–10%
  • • Ferrous Bisglycinate: 10%
  • • Ferrous Fumarate: 10%
  • • Ferric Pyrophosphates: 7% & 10%
Powder

IRONNOX™ Core Benefits

Supports haemoglobin & ferritin

Lowers anemia risk

Enhances energy & stamina

Why Ironnox Logo is Superior?

Feature IRONNOX™ Liposomal Iron Conventional Iron
Absorption Technology DFS Technology™ advanced liposomal delivery Basic form low absorption
Cellular Update 2x higher (Caco-2 proven) Low, inconsistent
Stability TEM, Zeta validated uniform nanoscale liposomes Prone to degradation
GI Tolerance Gentle, reduces Oxidative stress GI discomfort & oxidative stress
Efficacy Faster Hb & ferritin restoration Slow & inconsistent response

Backed by External Peer Reviewed Research

Nature Health | Paediatric Research

STUDY YEAR | 2025 | Wael A. Bahbah et al.

Interventional impact of liposomal iron on iron-deficient children’s developmental outcomes: a randomized, double-blind, placebo-controlled trial.

Liposomal iron showed a favorable impact on the growth and developmental outcomes of iron-deficient children.

READ THE STUDY

Springer Nature | International Journal of Clinical Pharmacy

STUDY YEAR | 2020 | C. V. A. Antunes et al.

Treatment of iron deficiency anemia with liposomal iron in inflammatory bowel disease: efficacy and impact on quality of life.

Oral liposomal iron was effective in improving mild iron deficiency anemia and enhancing quality of life.

READ THE STUDY

Wiley | European Journal of Haematology

STUDY YEAR | 2022 | Jamie O. Lo et al.

The role of oral iron in the treatment of adults with iron deficiency.

Oral iron effectively restores iron levels in individuals with iron deficiency.

READ THE STUDY

Wiley | Anaesthesia

STUDY YEAR | 2021 | C. S. Benson et al.

The effect of iron deficiency and anemia on women’s health.

Iron supplementation helps prevent and treat iron deficiency and anemia in women, improving energy levels, cognitive function, and maternal health outcomes.

READ THE STUDY

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